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Overview
The fixed combination of emtricitabine / rilpivirine / tenofovir alafenamide (trade name: Odefsey) has been approved in Germany since June 2016 for the treatment of type 1 HIV in adults and children aged 12 and over. more...
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Dolutegravir for first-line treatment of HIV in adults. In the spring of 2014 the Institute for Quality and Efficiency in Health Care (IQWiG, Germany) assessed which advantages and disadvantages dolutegravir has compared with previous standard therapies in people who are having initial treatment for HIV. more...
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Frequency of AIDS-related illnesses: A weakened immune system caused by an HIV infection makes a number of illnesses such as certain bacterial, viral or fungal infections more likely. The success of a particular treatment can be measured by whether these illnesses are less common. In the study, AIDS broke out in about 8 out of 1000 people ... more...
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Overview
Without treatment, the immune system is weakened so much by the HIV infection that serious diseases arise. This stage is called “AIDS” (acquired immunodeficiency syndrome). Although the currently available medications can't cure HIV, they can prevent immunodeficiency permanently. more...
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Yeast infections are also considered to be complicated if they’re caused by a weakened immune system, for instance due to an HIV infection. When treating complicated vaginal yeast infections, an initial treatment is typically followed by maintenance treatment. In the initial phase of treatment, creams or suppositories are used for 1 to 2 ... more...
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Overview
The fixed combination emtricitabine / tenofovir alafenamide (trade name: Descovy) has been approved in Germany since April 2016 for the treatment of human immunodeficiency virus (HIV) type 1 infection in adults and adolescents over 12 years of age. more...
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The patients did not also have an HIV infection. For this group, IQWiG performed a historical comparison with data from a total of nine studies. Five of these studies looked into treatment with ledipasvir / sofosbuvir and the other four examined the triple therapy with peginterferon alfa, ribavirin, and boceprevir or telaprevir. more...
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Research summaries
Oral thrush is a common side effect of cancer treatment. Find out which antifungal medications can prevent it. more...
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Treatments and diagnostic tests
Personalized medicine is based on these biological markers, also known as "biomarkers." Many biomarkers were only discovered in the last few years. So, nowadays, personalized medicine actually means using a specific combination of tests and treatments. Depending on the test results, a specific treatment will be recommended. Example: Malignant ... more...
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Fixed-dose combination of bictegravir / emtricitabine / tenofovir alafenamide (Biktarvy) as a subsequent treatment of HIV. In 2018, the Institute for Quality and Efficiency in Health Care (IQWiG, Germany) wanted to find out whether the fixed-dose combination of bictegravir / emtricitabine / tenofovir alafenamide (trade name: Biktarvy) has any ... more...
