Do people with severe hemophilia benefit from preventive treatment?
People who have severe hemophilia A may benefit from regular injections of clotting factors as a preventive treatment. This may lower the risk of severe bleeding.
Severe hemophilia affects the blood's clotting ability so much that people who have it may start bleeding for no apparent reason. Minor injuries can then lead to major blood loss. It often causes internal bleeding too, which can result in organ and joint damage.
This is because people who have hemophilia lack a specific protein (called a clotting factor) that enables blood to clot. Depending on which clotting factor is missing, the person has either hemophilia A (lack of factor VIII) or hemophilia B (lack of factor IX).