Andric M, Kalff JC, Schwenk W et al. Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen (S1-Leitlinie). AWMF-Registernr.: 088-011. 2021.
D'Souza N, Hicks G, Beable R et al. Magnetic resonance imaging (MRI) for diagnosis of acute appendicitis. Cochrane Database Syst Rev 2021; (12): CD012028.
Di Saverio S, Podda M, De Simone B et al. Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines. World J Emerg Surg 2020; 15(1): 27.
Fawkner-Corbett D, Hayward G, Alkhmees M et al. Diagnostic accuracy of blood tests of inflammation in paediatric appendicitis: a systematic review and meta-analysis. BMJ open 2022; 12(11): e056854.
Gorter RR, Eker HH, Gorter-Stam MA et al. Diagnosis and management of acute appendicitis. EAES consensus development conference 2015. Surg Endosc 2016; 30(11): 4668-4690.
Herrod PJ, Kwok AT, Lobo DN. Randomized clinical trials comparing antibiotic therapy with appendicectomy for uncomplicated acute appendicitis: meta-analysis. BJS Open 2022; 6(4): zrac100.
Jaschinski T, Mosch CG, Eikermann M et al. Laparoscopic versus open surgery for suspected appendicitis. Cochrane Database Syst Rev 2018; (11): CD001546.
Kothadia JP, Katz S, Ginzburg L. Chronic appendicitis: uncommon cause of chronic abdominal pain. Therap Adv Gastroenterol 2015; 8(3): 160-162.
Low ZX, Bonney GK, So JB et al. Laparoscopic versus open appendectomy in pediatric patients with complicated appendicitis: a meta-analysis. Surg Endosc 2019; 33(12): 4066-4077.
Müller M. Chirurgie - Für Studium und Praxis 2020/21. Breisach: Medizinische Verlags- u. Informationsdienste.
Poprom N, Numthavaj P, Wilasrusmee C et al. The efficacy of antibiotic treatment versus surgical treatment of uncomplicated acute appendicitis: Systematic review and network meta-analysis of randomized controlled trial. Am J Surg 2019; 218(1): 192-200.
Poprom N, Wilasrusmee C, Attia J et al. Comparison of postoperative complications between open and laparoscopic appendectomy: An umbrella review of systematic reviews and meta-analyses. J Trauma Acute Care Surg 2020; 89(4): 813-820.
Prechal D, Damirov F, Grilli M et al. Antibiotic therapy for acute uncomplicated appendicitis: a systematic review and meta-analysis. Int J Colorectal Dis 2019; 34(6): 963-971.
Talan DA, Di Saverio S. Treatment of Acute Uncomplicated Appendicitis. N Engl J Med 2021; 385(12): 1116-1123.
Téoule P, Laffolie J, Rolle U et al. Acute Appendicitis in Childhood and Adulthood. Dtsch Arztebl Int 2020; 117(45): 764-774.
Van Dijk ST, van Dijk AH, Dijkgraaf MG et al. Meta-analysis of in-hospital delay before surgery as a risk factor for complications in patients with acute appendicitis. Br J Surg 2018; 105(8): 933-945.
Yang Z, Sun F, Ai S et al. Meta-analysis of studies comparing conservative treatment with antibiotics and appendectomy for acute appendicitis in the adult. BMC Surg 2019; 19(1): 110.
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