Barthelsson C, Lützen K, Anderberg B, Bringman S, Nordström G. Patients' experiences of laparoscopic fundoplication in day surgery. Ambul Surg 2003; 10(2): 101-107.
Boghossian TA, Rashid FJ, Thompson W, Welch V, Moayyedi P, Rojas-Fernandez C et al. Deprescribing versus continuation of chronic proton pump inhibitor use in adults. Cochrane Database Syst Rev 2017; (3): CD011969.
Bundesinstitut für Arzneimittel und Medizinprodukte (BfArM). Protonenpumpeninhibitoren (verschreibungspflichtige Formen): Risiko von Knochenbrüchen sowie von Hypomagnesiämie, Aufforderung zur Textanpassung. July 26, 2012.
Dent J, Jones R, Kahrilas P, Talley NJ. Management of gastro-oesophageal reflux disease in general practice. BMJ 2001; 322(7282): 344-347.
Dibley LB, Norton C, Jones R. Don't eat tomatoes: patient's self-reported experiences of causes of symptoms in gastro-oesophageal reflux disease. Fam Pract 2010; 27(4): 410-417.
Eom CS, Park SM, Myung SK, Yun JM, Ahn JS. Use of acid-suppressive drugs and risk of fracture: a meta-analysis of observational studies. Ann Fam Med 2011; 9(3): 257-267.
Garg SK, Gurusamy KS. Laparoscopic fundoplication surgery versus medical management for gastro-oesophageal reflux disease (GORD) in adults. Cochrane Database Syst Rev 2015; (11): CD003243.
Ip S, Chung M, Moorth D, Yu WW, Lee J, Chan JA et al. Comparative effectiveness of management strategies for gastroesophageal reflux disease: update. (AHRQ Comparative Effectiveness Reviews; Volume 29).
Johnstone J, Nerenberg K, Loeb M. Meta-analysis: proton pump inhibitor use and the risk of community-acquired pneumonia. Aliment Pharmacol Ther 2010; 31(11): 1165-1177.
Jones R, Hunt C, Stevens R, Dalrymple J, Driscoll R, Sleet S et al. Management of common gastrointestinal disorders: quality criteria based on patients'views and practice guidelines. Br J Gen Pract 2009; 59(563): e199-208.
Kahrilas PJ, Howden CW, Hughes N. Response of regurgitation to proton pump inhibitor therapy in clinical trials of gastroesophageal reflux disease. Am J Gastroenterol 2011; 106(8): 1419-1425; quiz 1426.
Koop H, Fuchs KH, Labenz J, Lynen Jansen P, Messmann H, Miehlke S et al. Gastroösophageale Refluxkrankheit (S2k-Leitinie). AWMF-Registernr.: 021-013. 05.2014.
Kwok CS, Yeong JK, Loke YK. Meta-analysis: risk of fractures with acid-suppressing medication. Bone 2011; 48(4): 768-776.
Leiman DA, Riff BP, Morgan S, Metz DC, Falk GW, French B et al. Alginate therapy is effective treatment for GERD symptoms: a systematic review and meta-analysis. Dis Esophagus 2017; 30(5): 1-9.
Rickenbacher N, Kotter T, Köchen MM, Scherer M, Blozik E. Fundoplication versus medical management of gastroesophageal reflux disease: systematic review and meta-analysis. Surg Endosc 2014; 28(1): 143-155.
Sigterman KE, van Pinxteren B, Bonis PA, Lau J, Numans ME. Short-term treatment with proton pump inhibitors, H2-receptor antagonists and prokinetics for gastro-oesophageal reflux disease-like symptoms and endoscopy negative reflux disease. Cochrane Database Syst Rev 2013; (5): CD002095.
Song H, Zhu J, Lu D. Long-term proton pump inhibitor (PPI) use and the development of gastric pre-malignant lesions. Cochrane Database Syst Rev 2014; (12): CD010623.
Sun S, Cui Z, Zhou M, Li R, Li H, Zhang S et al. Proton pump inhibitor monotherapy and the risk of cardiovascular events in patients with gastro-esophageal reflux disease: a meta-analysis. Neurogastroenterol Motil 2017; 29(2).
Wang Y, Pan T, Wang Q, Guo Z. Additional bedtime H2-receptor antagonist for the control of nocturnal gastric acid breakthrough. Cochrane Database Syst Rev 2009; (4): CD004275.
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