Bleakley CM, McDonough SM, MacAuley DC. Some conservative strategies are effective when added to controlled mobilisation with external support after acute ankle sprain: a systematic review. Aust J Physiother 2008; 54(1): 7-20.
De Vries JS, Krips R, Sierevelt IN et al. Interventions for treating chronic ankle instability. Cochrane Database Syst Rev 2011; (8): CD004124.
Derry S, Moore RA, Gaskell H et al. Topical NSAIDs for acute musculoskeletal pain in adults. Cochrane Database Syst Rev 2015; (6): CD007402.
Feger MA, Herb CC, Fraser JJ et al. Supervised rehabilitation versus home exercise in the treatment of acute ankle sprains: a systematic review. Clin Sports Med 2015; 34(2): 329-346.
Hansrani V, Khanbhai M, Bhandari S et al. The role of compression in the management of soft tissue ankle injuries: a systematic review. Eur J Orthop Surg Traumatol 2015; 25(6): 987-995.
Kerkhoffs GM, Handoll HH, de Bie R et al. Surgical versus conservative treatment for acute injuries of the lateral ligament complex of the ankle in adults. Cochrane Database Syst Rev 2007; (2): CD000380.
Miranda JP, Silva WT, Silva HJ et al. Effectiveness of cryotherapy on pain intensity, swelling, range of motion, function and recurrence in acute ankle sprain: A systematic review of randomized controlled trials. Phys Ther Sport 2021; 49: 243-249.
Nunes GS, Feldkircher JM, Tessarin BM et al. Kinesio taping does not improve ankle functional or performance in people with or without ankle injuries: Systematic review and meta-analysis. Clin Rehabil 2021; 35(2): 182-199.
Southerst D, Yu H, Randhawa K et al. The effectiveness of manual therapy for the management of musculoskeletal disorders of the upper and lower extremities: a systematic review by the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration. Chiropr Man Therap 2015; 23: 30.
Struijs PA, Kerkhoffs GM. Ankle sprain. BMJ Clin Evid 2010.
Struijs PA, Kerkhoffs GM. Ankle sprain: the effects of non-steroidal anti-inflammatory drugs. BMJ Clin Evid 2015: pii: 1115.
Van den Bekerom MP, van der Windt DA, Ter Riet G et al. Therapeutic ultrasound for acute ankle sprains. Cochrane Database Syst Rev 2011; (6): CD001250.
Woitzik E, Jacobs C, Wong JJ et al. The effectiveness of exercise on recovery and clinical outcomes of soft tissue injuries of the leg, ankle, and foot: A systematic review by the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration. Manual Ther 2015; 20(5): 633-645.
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