Bleakley CM, McDonough SM, MacAuley DC. Some conservative strategies are effective when added to controlled mobilisation with external support after acute ankle sprain: a systematic review. Aust J Physiother 2008; 54(1): 7-20.
De Vries JS, Krips R, Sierevelt IN, Blankevoort L, van Dijk CN. Interventions for treating chronic ankle instability. Cochrane Database Syst Rev 2011; (8): CD004124.
Derry S, Moore RA, Gaskell H, McIntyre M, Wiffen PJ. Topical NSAIDs for acute musculoskeletal pain in adults. Cochrane Database Syst Rev 2015; (6): CD007402.
Feger MA, Herb CC, Fraser JJ, Glaviano N, Hertel J. Supervised rehabilitation versus home exercise in the treatment of acute ankle sprains: a systematic review. Clin Sports Med 2015; 34(2): 329-346.
Hansrani V, Khanbhai M, Bhandari S, Pillai A, McCollum CN. The role of compression in the management of soft tissue ankle injuries: a systematic review. Eur J Orthop Surg Traumatol 2015; 25(6): 987-995.
Kerkhoffs GM, Handoll HH, de Bie R, Rowe BH, Struijs PA. Surgical versus conservative treatment for acute injuries of the lateral ligament complex of the ankle in adults. Cochrane Database Syst Rev 2007; (2): CD000380.
Southerst D, Yu H, Randhawa K, Cote P, D'Angelo K, Shearer HM et al. The effectiveness of manual therapy for the management of musculoskeletal disorders of the upper and lower extremities: a systematic review by the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration. Chiropr Man Therap 2015; 23: 30.
Struijs PA, Kerkhoffs GM. Ankle sprain. BMJ Clin Evid 2010.
Struijs PA, Kerkhoffs GM. Ankle sprain: the effects of non-steroidal anti-inflammatory drugs. BMJ Clin Evid 2015: pii: 1115.
van den Bekerom MP, van der Windt DA, Ter Riet G, van der Heijden GJ, Bouter LM. Therapeutic ultrasound for acute ankle sprains. Cochrane Database Syst Rev 2011; (6): CD001250.
Woitzik E, Jacobs C, Wong JJ, Cote P, Shearer HM, Randhawa K et al. The effectiveness of exercise on recovery and clinical outcomes of soft tissue injuries of the leg, ankle, and foot: A systematic review by the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration. Man Ther 2015; 20(5): 633-645.
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