Diverticular disease: How are chronic symptoms treated?

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Sometimes diverticula lead to ongoing or recurring symptoms, or infections. A change in diet and certain medications can sometimes relieve the symptoms. If that doesn't help enough, bowel surgery is an option.

Diverticula are small sac-like pouches that develop in the wall of the bowel. They often don't cause any symptoms, or only cause temporary symptoms that are easy to treat. But they can also cause problems over the long term. Chronic diverticular disease can be divided into two forms:

  • Symptomatic uncomplicated diverticular disease (SUDD): This form is characterized by ongoing (chronic) or recurrent symptoms such as pain, bloating and irregular bowel movements (poop). But there are rarely signs of or . The symptoms of SUDD are very similar to those of irritable bowel syndrome and it's often difficult to tell them apart, even after doing various examinations.
  • Recurrent diverticulitis: In this form, the diverticula keep becoming inflamed or infected. Although this doesn’t always lead to complications, it may result in collections of pus (abscesses) or narrowing of the bowel (intestinal stenosis).

It is not always possible to clearly differentiate between the two forms. Some people have both chronic symptoms and recurrent inflammations or infections. But the treatment options are different.

How is symptomatic uncomplicated diverticular disease treated?

The treatment options for SUDD include a change in diet, medication and surgery.

Diet

There is some initial to suggest that a high-fiber diet can reduce digestive problems caused by diverticular disease. This kind of diet mainly consists of a lot of fruit, grains, vegetables and legumes (e.g. beans and peas). It makes the stool (poop) softer, increases the volume of stool and stimulates digestion. This helps the stool move through the bowel faster and reduces the pressure on the wall of the bowel. Some people who have bowel problems add linseed and psyllium husk to their diet. These contain soluble fiber that binds to water in the bowel. Because of this, people who eat a lot of fiber are also advised to make sure they drink enough fluids.

The bowel contains different types of and other microorganisms (gut flora) that play an important role in how well it works and how healthy it is. These include lactic acid and bifidobacteria. Some people with diverticula have abnormal gut flora. For this reason, it is thought that probiotics containing "healthy" bacteria might be able to help. But it's not clear whether probiotics actually help in symptomatic uncomplicated diverticular disease.

Medications

The prescription-only medication mesalazine (also known as mesalamine) has been approved for use in the treatment of the chronic inflammatory bowel diseases known as and . If it is used in the treatment of diverticular disease, it has to be used “off-label.” It is usually taken every day for several months. Studies have suggested that it can relieve the symptoms in some people. Due to a lack of research, though, it's not yet possible to know for sure how effective mesalazine really is here.

Surgery

It is not clear whether bowel surgery can help in people with symptomatic uncomplicated diverticular disease. The procedure, in which part of the bowel is removed, is associated with risks such as organ injuries and bleeding. Because of this, surgery is not recommended for uncomplicated diverticular disease.

How is recurrent diverticulitis treated?

Each new episode of diverticulitis is treated like a first acute episode. Antibiotics are important in complicated diverticulitis, but they aren’t always needed in uncomplicated diverticulitis. Complicated diverticulitis (where pus-filled abscesses have formed) has to be treated in a hospital. Surgery is needed if there is an increased risk of serious complications such as peritonitis (inflamed inner lining of the belly) or blood poisoning (sepsis).

Various medications are sometimes used for the prevention of recurrent diverticulitis. These include antibiotics and mesalazine. When tested in studies, though, they weren’t found to effectively prevent inflammations or infections. Because of this, experts do not recommend taking them as a preventative measure. It is not clear whether a high-fiber diet helps to prevent recurrent diverticulitis.

Important:

Painkillers like ibuprofen or diclofenac (NSAIDs: non-steroidal ) shouldn’t be used to treat diverticulitis because they can increase the likelihood of complications such as an intestinal perforation (a hole in the wall of the bowel). If necessary, other painkillers can be considered.

If the symptoms are a big problem over the long term, surgery may be considered. This involves removing a part of the bowel. The procedure can relieve the symptoms and reduce the risk of further or infections. But it's quite unlikely to prevent complications of diverticulitis. The reason for this: Research has shown that the risk of complications is highest the first time you have diverticulitis. It is a lot lower when you have further episodes. After the fifth episode, it is less than 1%.

Surgery is associated with risks such as organ injuries, though, so it's important to carefully weigh up the pros and cons of this treatment option.

Balk EM, Adam GP, Cao W et al. Management of Colonic Diverticulitis. (AHRQ Comparative Effectiveness Reviews; No. 233). 2020.

Carabotti M, Annibale B, Severi C et al. Role of Fiber in Symptomatic Uncomplicated Diverticular Disease: A Systematic Review. Nutrients 2017; 9(2): 161.

Kertzman BA, Amelung FJ, Bolkenstein HE et al. Does surgery improve quality of life in patients with ongoing- or recurrent diverticulitis; a systematic review and meta-analysis. Scand J Gastroenterol 2024; 59(7): 770-780.

Lahner E, Bellisario C, Hassan C et al. Probiotics in the Treatment of Diverticular Disease. A Systematic Review. J Gastrointestin Liver Dis 2016; 25(1): 79-86.

Leifeld L, Germer CT, Bohm S et al. S3-Leitlinie Divertikelkrankheit / Divertikulitis. Gemeinsame Leitlinie der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft für Allgemein- und Viszeralchirurgie (DGAV). AWMF register no.: 021-020. 2021.

Morris AM, Regenbogen SE, Hardiman KM et al. Sigmoid diverticulitis: a systematic review. JAMA 2014; 311(3): 287-297.

Picchio M, Elisei W, Brandimarte G et al. Mesalazine for the Treatment of Symptomatic Uncomplicated Diverticular Disease of the Colon and for Primary Prevention of Diverticulitis: A Systematic Review of Randomized Clinical Trials. J Clin Gastroenterol 2016; 50 (Suppl 1): S64-69.

IQWiG health information is written with the aim of helping people understand the advantages and disadvantages of the main treatment options and health care services.

Because IQWiG is a German institute, some of the information provided here is specific to the German health care system. The suitability of any of the described options in an individual case can be determined by talking to a doctor. informedhealth.org can provide support for talks with doctors and other medical professionals, but cannot replace them. We do not offer individual consultations.

Our information is based on the results of good-quality studies. It is written by a team of health care professionals, scientists and editors, and reviewed by external experts. You can find a detailed description of how our health information is produced and updated in our methods.

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Updated on February 9, 2026

Next planned update: 2029

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Institute for Quality and Efficiency in Health Care (IQWiG, Germany)

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