Stroke

At a glance

  • A stroke happens when the blood supply to part of the brain is disrupted – usually due to a clot blocking a blood vessel.
  • Common symptoms include paralysis and speech problems.
  • A stroke is an emergency – it’s very important to have a stroke treated quickly to prevent permanent damage.
  • Rehabilitation helps ease the effects of a stroke.
  • Controlling risk factors, like high blood pressure, can prevent stroke.

Introduction

Photo of man sitting with a dog

Sudden paralysis, problems with eyesight and speech, and occasionally headache are the usual signs of a stroke. The exact symptoms mostly depend on what part of the brain is affected.

The cause of a stroke is a clot blocking a blood vessel in the brain or bleeding in the brain (brain hemorrhage). A stroke is often referred to as a cerebral infarction.

Important:

A stroke is a medical emergency that requires immediate treatment. If you think someone is having a stroke, call emergency services immediately (112 in Germany and many other countries or 911 in the U.S.).

Symptoms

The following are common signs of a stroke:

  • A sudden feeling of weakness
  • Numbness and paralysis
  • Language disorders
  • Vision problems
  • Dizziness and trouble walking

Some people also have severe headaches, along with nausea, vomiting and unconsciousness.

Usually, only one side of the body is affected, making it impossible to move the right arm and/or right leg, for example. Drooping on one side of the mouth is another typical sign of a stroke.

Causes

In most cases, strokes are caused by a blood clot that is blocking a blood vessel in the brain. The clot usually forms in the carotid arteries or the heart. It then flows into the brain, where it blocks a blood vessel. A stroke that is caused by a blocked blood vessel is referred to as an ischemic stroke.

Bleeding (hemorrhage) in the brain is the second, less common cause. This occurs if, for instance, a blood vessel ruptures and blood leaks into the brain tissue.

In both cases, one part of the brain is no longer supplied with enough oxygen. Bleeding also increases the pressure on the brain tissue, which can cause additional damage. The sooner the treatment is started and the oxygen supply is restored, the better the chances are of minimizing damage to the brain.

Risk factors

It is very uncommon for blood clots to develop in the blood vessels of healthy people. But certain conditions, habits and genetic factors can increase the risk of a stroke. These include, for example, smoking, lack of exercise, severe obesity, high blood pressure, high cholesterol, narrowing of the carotid artery (carotid artery stenosis) and atrial fibrillation.

Typical signs of a stroke that then go away on their own after a few hours may be signs of a transient ischemic attack (TIA). This happens when a blood clot forms but then breaks up again before the brain is damaged more severely. People who have had a transient ischemic attack (TIA) are more likely to have a stroke.

Prevalence

About 3 out of 100 people have a stroke at some point in their lives. The risk increases with age: Most of the people who have a stroke are over 60. Men and women are affected at about the same rate.

Effects

Most people survive strokes. But they can result in the following impairments:

  • Paralysis on one side of the body
  • Muscle spasms
  • Trouble swallowing
  • Language disorders
  • Problems paying attention and concentrating
  • Vision problems
  • Lack of awareness of the affected side of the body (neglect)
  • Mental health problems like or anxiety

Some people who’ve had a stroke need nursing care or support in their everyday lives.

Symptoms such as paralysis often get better over time, but they can also be permanent. Around 40 out of 100 people who survive a stroke have severe permanent impairments as a result. They may come to rely on other people a lot or need long-term nursing care.

And people who have had a stroke are also at greater risk of having another. About 7 out of 100 people who survive a stroke have another one within the space of a year. Other cardiovascular diseases, such as heart attacks, are also more likely to occur in people who have had a stroke. Around 17 out of 100 people die within one year of having a stroke.

Diagnosis

A stroke is a medical emergency. If you think you or somebody else might be having a stroke you should call for an ambulance immediately (112 in Germany and many other countries or 911 in the U.S.). Do not wait to see if the symptoms go away.

After the paramedics have examined the patient, he or she will be taken to hospital - if possible, one that specializes in strokes. There, comprehensive testing can be started immediately, so that the cause of the symptoms can be determined and treatment can be started soon afterwards. The tests typically include (CT) or (MRI).

Prevention

Not smoking significantly reduces the risk of cardiovascular disease such as a stroke. Regular exercise can also help to lower the risk. Whether or not particular preventive measures against a stroke are worthwhile will depend on whether the person has any other conditions and risk factors.

People with high blood pressure can reduce their risk of a stroke by taking blood-pressure-lowering medication. Anticoagulants are an option for people who are at greater risk of blood clots forming – for example, if they have . Cholesterol-lowering medication () can also help prevent stroke.

These precautions can be helpful for people who’ve already had a stroke too because they lower the risk of a repeat stroke.

Sometimes, the doctor will recommend surgery to unblock blood vessels in a carotid artery for instance. If the blockage is severe and the symptoms are persistent, another option is to insert a stent. Stents are wire-mesh tubes used to ensure blood vessels stay open. But it is important to carefully consider the pros and cons of this type of surgery.

Treatment

Acute treatment aims to save a person's life and minimize damage as much as possible. The type of treatment will mainly depend on whether the stroke was caused by a blood clot or a hemorrhage.

If it was a clot, the doctors will try to unblock the vessel as quickly as possible. There are two ways of doing this: Thrombolysis and thrombectomy. Thrombolysis involves taking medication via a drip to dissolve the clot. Thrombectomy is a procedure to remove the clot from blood vessels in the brain using a . If possible, the doctor will use a combination of these two methods. They are intended to unblock the blood vessel before permanent damage occurs, so they can only be used within a few hours of the first symptoms starting. That’s why it’s so important to get hospital treatment for a stroke quickly. Specialized stroke units at the hospital are the best place to go.

Brain hemorrhages have to be stopped quickly, sometimes by operating.

Further treatment and need for observation depend on the severity of the stroke, the effects it had, and the results of further examinations. Rehabilitation is started as soon as possible.

Rehabilitation

Most people find it very important to regain their mobility, muscle strength, speech, and independence after having a stroke. Restoring emotional balance is also key. Rehabilitation usually begins when the person is still being treated in hospital. It can be continued after in a special clinic or as an outpatient.

There are various rehabilitation programs with different contents. Depending on the person’s needs, rehabilitation focuses on physical therapy and fitness training, speech therapy and swallowing exercises. The goal is to reduce the physical symptoms and/or learn how to cope with them. Occupational therapy involves learning how to successfully cope with challenges in daily life as well as possible, despite the limitations.

Everyday life

It is normal for people to feel sad and depressed after a stroke. Depending on how severe it was, it can have an enormous impact on a person's life.

People who used to live independently and now have to rely on others for help have to come to terms with the effects of the stroke – both the psychological consequences as well as the practical challenges in everyday situations.

Treatment and rehabilitation can help people to regain some of their independence after a stroke. Over time, most patients and their families manage to adapt their lives to the changes as best they can.

But some people develop depression as a result of a stroke, and need professional help for it. Often, it goes unnoticed or people think it’s a normal reaction and don’t take any action to treat it. Apart from the impact on mental health, can prevent proper physical recovery too. It's important that stroke patients and their families receive the support that they need to prevent , or are offered help if has already set in.

Further information

A lot of support is available for people who have had a stroke, as well as for their families. For instance, there are special information centers and self-help groups that can provide patients and their families with help concerning nursing care, finances and psychosocial issues. The available services will depend on the center and can’t always be found immediately. We have put together a list of places that you can contact to find out where you can get help (in Germany only).

Good to know:

Resources for people who have had a stroke and their families can also be found on the German Stroke Foundation (Deutsche Schlaganfall-Hilfe) website (in German).

Many cities, local authorities and welfare associations in Germany have special centers that provide information on nursing care, free of charge. The Centre for Quality in Care (Zentrum für Qualität in der Pflege, ZQP) has a database on its website that allows users to search for local information centers for caregivers (in German). Family members can also take nursing care courses to learn things like basic care techniques.

Feigin VL, Brainin M, Norrving B et al. World Stroke Organization: Global Stroke Fact Sheet 2025. Int J Stroke 2025; 20(2): 132-144.

Forshing L, Mahammed Z, Khan S et al. Ischemic Stroke. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2025.

Furie KL, Kelly PJ. Secondary Prevention after Ischemic Stroke. N Engl J Med 2026; 394(8): 784-792.

GBD 2021 Stroke Risk Factor Collaborators. Global, regional, and national burden of stroke and its risk factors, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet Neurol 2024; 23(10): 973-1003.

Knecht S, Hesse S, Oster P. Rehabilitation after stroke. Dtsch Arztebl Int 2011; 108(36): 600-606.

National Institute for Health and Care Excellence (NICE). Stroke and transient ischaemic attack. 2022.

National Institute for Health and Care Excellence (NICE). Stroke rehabilitation in adults. 2023.

Robert Koch-Institut (RKI). Schlaganfall: Prävalenz (ab 18 Jahre). 2025.

Robinson RG, Jorge RE. Post-Stroke Depression: A Review. Am J Psychiatry 2016; 173(3): 221-231.

Stahmeyer JT, Stubenrauch S, Geyer S et al. The Frequency and Timing of Recurrent Stroke: An Analysis of Routine Health Insurance Data. Dtsch Arztebl Int 2019; 116(42): 711-717.

IQWiG health information is written with the aim of helping people understand the advantages and disadvantages of the main treatment options and health care services.

Because IQWiG is a German institute, some of the information provided here is specific to the German health care system. The suitability of any of the described options in an individual case can be determined by talking to a doctor. informedhealth.org can provide support for talks with doctors and other medical professionals, but cannot replace them. We do not offer individual consultations.

Our information is based on the results of good-quality studies. It is written by a team of health care professionals, scientists and editors, and reviewed by external experts. You can find a detailed description of how our health information is produced and updated in our methods.

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Updated on September 17, 2026

Next planned update: 2029

Publisher:

Institute for Quality and Efficiency in Health Care (IQWiG, Germany)

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