Danishyar A, Ashurst JV. Acute Otitis Media. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2023.
Darlison P, Moresco L, Nussbaumer-Streit B et al. Decongestants and antihistamines for acute otitis media in children. Cochrane Database Syst Rev 2025; (11): CD015839.
De Sévaux JL, Damoiseaux RA, van de Pol AC et al. Paracetamol (acetaminophen) or non-steroidal anti-inflammatory drugs, alone or combined, for pain relief in acute otitis media in children. Cochrane Database Syst Rev 2023; (8): CD011534.
De Sévaux JL, Venekamp RP, Lutje V et al. Pneumococcal conjugate vaccines for preventing acute otitis media in children. Cochrane Database Syst Rev 2020; (11): CD001480.
Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie (DGHNO-KHC). S2k-Leitlinie Antibiotikatherapie bei HNO-Infektionen. 2025.
Jones LL, Hassanien A, Cook DG et al. Parental smoking and the risk of middle ear disease in children: a systematic review and meta-analysis. Arch Pediatr Adolesc Med 2012; 166(1): 18-27.
Nelson AM. A comprehensive review of evidence and current recommendations related to pacifier usage. J Pediatr Nurs 2012; 27(6): 690-699.
Norhayati MN, Ho JJ, Azman MY. Influenza vaccines for preventing acute otitis media in infants and children. Cochrane Database Syst Rev 2017; (10): CD010089.
Shaikh N. Otitis Media in Young Children. N Engl J Med 2025; 392(14): 1418-1426.
Son MJ, Choi S, Kim YE et al. Herbal medicines for the treatment of otitis media with effusion: a systematic review of randomised controlled trials. BMJ Open 2016; 6(11): e011250.
Son MJ, Kim YE, Song YI et al. Herbal medicines for treating acute otitis media: A systematic review of randomised controlled trials. Complement Ther Med 2017; 35: 133-139.
Venekamp RP, Mick P, Schilder AG et al. Grommets (ventilation tubes) for recurrent acute otitis media in children. Cochrane Database Syst Rev 2018; (5): CD012017.
Venekamp RP, Sanders SL, Glasziou PP et al. Antibiotics for acute otitis media in children. Cochrane Database Syst Rev 2023; (11): CD000219.
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